NIEUWEGEIN, Netherlands (AP) — International prosecutors announced murder charges Wednesday against four men — three of them Russians with military or intelligence backgrounds — in the missile attack that blew a Malaysia Airlines jet out of the sky over Ukraine five years ago, killing all 298 people aboard.

The case, built with the help of wiretaps, radar images and social media posts, marks the most significant step yet toward tying the tragedy to Moscow, which has backed the pro-Russian separatists fighting to seize control of eastern Ukraine.

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